If you’re craving a dish that combines creamy mac and cheese with savory meatloaf, this Mac and Cheese Meatloaf Casserole is the perfect meal. This easy-to-make casserole is rich, hearty, and filled with flavors that are sure to satisfy. Whether you’re cooking for a weeknight dinner or a family gathering, this recipe is sure to be a hit.

This comforting dish combines a cheesy pasta layer with a savory meatloaf base, offering both texture and flavor in every bite. If you’re a fan of classic comfort food, you’ll love how this casserole comes together quickly, making it a great choice for those busy nights when you still want something homemade and delicious.

For an even more unique twist on classic flavors, you might also want to try other comfort dishes like this Cheese Steak Tortellini in Rich Provolone Sauce, which takes cheesy goodness to another level.

Why You’ll Love Mac and Cheese Meatloaf Casserole

This casserole is the ultimate comfort food mashup. The combination of a savory meatloaf layer topped with gooey mac and cheese makes it a filling, satisfying meal. It’s the perfect dish for feeding a crowd or enjoying as leftovers throughout the week.

• Rich, creamy texture: The cheese adds a layer of creaminess, while the meatloaf brings a savory element to the dish.
• Customizable: You can switch up the cheeses or meat, and even make it gluten-free for dietary preferences.
• Versatile: This dish is easy to prep ahead and can be frozen for later.

For more tips on crafting the perfect one-pan meal with cheesy flavors, check out this recipe for Garlic Butter Chicken with Parmesan Rice, another great comfort food option.

Essential Ingredients for Mac and Cheese Meatloaf Casserole

Here’s what you’ll need to make this delicious Mac and Cheese Meatloaf Casserole:

Meatloaf Base:

• 2 lbs lean ground beef (or substitute with ground turkey or pork)
• Ritz Crackers or breadcrumbs for binding
• Lipton onion soup mix for added flavor
• 2 eggs to hold the meatloaf together
• 1 cup ketchup and 1 cup BBQ sauce for a tangy glaze

Mac and Cheese Layer:

• 3 cups macaroni noodles (cooked al dente)
• 2 cups milk and 1 can condensed cheddar cheese soup for a creamy base
• 4 cups shredded cheese (cheddar or mozzarella works best)
• Salt, pepper, garlic powder, and onion powder to season

Optional Additions:

• Bacon bits for extra flavor
• Jalapenos if you like some heat
• A crunchy breadcrumb topping for added texture

Step-by-Step Instructions for Making Mac and Cheese Meatloaf Casserole

1. Preheat the Oven

Set your oven to 350°F and grease a 9×13 inch baking dish. This ensures that your casserole bakes evenly and doesn’t stick to the pan.

2. Prepare the Meatloaf

• In a large bowl, mix the ground beef, crushed Ritz Crackers, Lipton onion soup mix, and eggs.
• Add half the ketchup and BBQ sauce to the mixture for flavor.
• Press the meatloaf mixture into the greased baking dish, ensuring it’s spread evenly. This will serve as the base layer of the casserole.

3. Bake the Meatloaf

• Spread the remaining ketchup and BBQ sauce over the top of the meatloaf for a tangy glaze.
• Bake for 30 minutes.

4. Prepare the Mac and Cheese

• While the meatloaf is baking, cook the macaroni according to package instructions. Drain and set aside.
• In a large bowl, whisk together milk and condensed cheddar cheese soup. Season with salt, pepper, garlic powder, and onion powder.
• Stir in the cooked macaroni and 2 cups of shredded cheese.

5. Assemble the Casserole

• Remove the meatloaf from the oven and pour the mac and cheese mixture over the top.
• Sprinkle the remaining shredded cheese on top to create a cheesy, gooey topping.

6. Final Bake

• Return the dish to the oven and bake for an additional 17-20 minutes, or until the cheese on top is melted and golden. If you like a crispy cheese topping, broil the casserole for the last few minutes.

7. Let it Rest

Before serving, let the casserole rest for 5-10 minutes. This allows the layers to set, making it easier to slice and serve.

Recipe Variations and Customizations

This Mac and Cheese Meatloaf Casserole is easy to customize to fit your taste. Here are a few ideas:

• Cheese Variations: Try using Monterey Jack, Colby Jack, or even smoked gouda to change the flavor profile.
• Meat Substitutions: You can use ground turkey, chicken, or even a mix of pork and beef for the meatloaf base.
• Vegetarian Option: Use a plant-based meat alternative and a dairy-free cheese for a vegetarian version.
• Gluten-Free Version: Use gluten-free crackers or breadcrumbs, gluten-free pasta, and gluten-free soup mix to make the dish gluten-free. For more inspiration on how to adapt this recipe, see these gluten-free meatloaf tips.

Serving Suggestions for Mac and Cheese Meatloaf Casserole

This casserole is hearty enough to be served on its own, but you can elevate the meal with some complementary side dishes:

• Steamed vegetables like broccoli or green beans to balance the richness.
• Garlic bread to soak up the cheesy goodness.
• A tangy coleslaw to cut through the heaviness.
• A simple green salad with vinaigrette for a lighter side.

Nutritional Information

Here’s an approximate nutritional breakdown for one serving of Mac and Cheese Meatloaf Casserole:

• Calories: 600-700 kcal
• Protein: 35-40g
• Carbohydrates: 45-50g
• Fat: 30-35g (15g saturated fat)
• Sodium: 1200-1400mg

To reduce the calorie count, use lean ground meat, reduced-fat cheese, or low-sodium soup and ketchup options.

FAQs

Can I make Mac and Cheese Meatloaf Casserole ahead of time?
Yes! You can assemble the casserole and refrigerate it until you’re ready to bake. Just add an extra 10-15 minutes to the baking time if it’s coming straight from the fridge.

Can I freeze this casserole?
Absolutely. You can freeze the casserole before or after baking. If freezing before baking, be sure to thaw it overnight in the fridge before cooking.

How do I store leftovers?
Leftovers can be stored in an airtight container in the fridge for up to 3 days. Reheat in the oven at 350°F to maintain the texture and flavor.

How can I make this dish gluten-free?
To make this dish gluten-free, use gluten-free crackers, pasta, and soup mix. Check out this guide on gluten-free meatloaf tips for more ideas.

Conclusion

This Mac and Cheese Meatloaf Casserole is a delicious blend of two comfort food classics, offering a rich, cheesy topping over a savory meatloaf base. Whether you’re feeding a family or making a meal for leftovers, this casserole will become a favorite in your dinner rotation. With its customizable ingredients and make-ahead convenience, you can easily adapt this dish to suit your needs. So why not give it a try and enjoy the best of both worlds in one dish?